Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9UKA9 / PTBP2_HUMAN
Protein Name Polypyrimidine tract-binding protein 2
Gene Name Name: PTBP2
Organism Homo sapiens (Human)

DAG View
PRO Name polypyrimidine tract-binding protein 2 (human)
Definition A polypyrimidine tract-binding protein 2 that is encoded in the genome of human.
Short Label hPTBP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9UKA9 (PTBP2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378
N31 N-Glycosylation GlyGen 29671580
S34 Phosphorylation PhosphoSitePlus
T38 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K84 Sumoylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus
K137 Sumoylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
K215 Sumoylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus   UniProt 20068231
K429 Ubiquitination PhosphoSitePlus
S434 Phosphorylation PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
K528 Acetylation PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
T530 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation HPRD 20068231
S26 Phosphorylation HPRD 20068231
S27 Phosphorylation HPRD 20068231
S33 Phosphorylation HPRD 20068231
S34 Phosphorylation HPRD 20068231
T38 Phosphorylation HPRD 20068231
S308 Phosphorylation HPRD 20068231
S377 Phosphorylation HPRD 20068231
S434 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S313 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S27 I27 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S34 I34 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S44 I44 Biomuta DOID:363 / uterine cancer [ tcga ]
K84 E84 Biomuta DOID:1324 / lung cancer [ tcga ]
S269 T269 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S444 F444 Biomuta DOID:1909 / melanoma [ icgc, tcga ]