Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9UKA2 / FBXL4_HUMAN
Protein Name F-box/LRR-repeat protein 4
Gene Name Name: FBXL4
Organism Homo sapiens (Human)

DAG View
PRO Name F-box/LRR-repeat protein 4 (human)
Definition An F-box/LRR-repeat protein 4 that is encoded in the genome of human.
Short Label hFBXL4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9UKA2 (FBXL4) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K115 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
T202 Phosphorylation PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
Y467 Phosphorylation PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus
K537 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T202 K202 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:1324 / lung cancer [ tcga ]
T238 N238 Biomuta DOID:3571 / liver cancer [ icgc ]
S460 R460 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]