Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKA1 / FBXL5_HUMAN
Protein Name F-box/LRR-repeat protein 5
Gene Name Name: FBXL5
Synonyms:FBL4,FBL5,FLR1;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKA1
DAG View
PRO Name F-box/LRR-repeat protein 5 (human)
Definition An F-box/LRR-repeat protein 5 that is encoded in the genome of human.
Short Label hFBXL5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKA1 (FBXL5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K94 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
K432 Ubiquitination PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
S566 Phosphorylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
K591 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y103 Phosphorylation HPRD 18452278
Y108 Phosphorylation HPRD 18452278


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9BQ15 (NABP2) T117 Q9UKA1 (FBXL5) inhibited_association eFIP 25249620


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K403 E403 Biomuta DOID:1319 / brain cancer [ icgc ]
K403 N403 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K434 R434 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]