iPTMnet Report for Q9UK76 (JPT1)
Protein Information
| UniProt AC / UniProt ID | Q9UK76 / JUPI1_HUMAN |
| Protein Name | Jupiter microtubule associated homolog 1 |
| Gene Name | Name: JPT1 Synonyms:ARM2,HN1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UK76 |
| PRO Name | jupiter microtubule associated homolog 1 (human) |
| Definition | A jupiter microtubule associated homolog 1 that is encoded in the genome of human. |
| Short Label | hJPT1 |
| Category | organism-gene |
Q9UK76 (JPT1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22814378 | ||
| T2 | Acetylation | score3 | UniProt | 22814378, 16602700 | ||
| K8 | Acetylation | score2 | IEDB PhosphoSitePlus | 34357683 | ||
| K8 | Methylation | score1 | PhosphoSitePlus | |||
| K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R22 | Methylation | score1 | PhosphoSitePlus | |||
| S28 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| N29 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| S31 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K46 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S49 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T54 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 18669648, 19690332, ... | ||
| S61 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
| S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K69 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S70 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S71 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S79 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S80 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S87 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 17081983, ... | ||
| S88 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 17081983, 18669648, ... | ||
| S91 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S92 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S115 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S119 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S131 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17081983, 20068231 | ||
| S140 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K148 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K148 | Methylation | score1 | PhosphoSitePlus | |||
| S149 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S150 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T2 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S17 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S31 | Phosphorylation | score0 | HPRD | 18212344 | ||
| T54 | Phosphorylation | score0 | HPRD | 19413330, 20058876, 18669648, ... | ||
| S70 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 17924679 | ||
| S71 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S79 | Phosphorylation | score0 | HPRD | 19651622 | ||
| S80 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 17924679 | ||
| S87 | Phosphorylation | score0 | HPRD | 17322306, 18578522, 18491316, ... | ||
| S88 | Phosphorylation | score0 | HPRD | 19413330, 17322306, 18491316, ... | ||
| S92 | Phosphorylation | score0 | HPRD | 19651622 | ||
| S131 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 17081983, ... | ||
| S140 | Phosphorylation | score0 | HPRD | 17081983 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T2 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S17 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S31 | Phosphorylation | score0 | HPRD | 18212344 | ||
| T54 | Phosphorylation | score0 | HPRD | 19413330, 20058876, 18669648, ... | ||
| K69 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S70 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 17924679 | ||
| S71 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S79 | Phosphorylation | score0 | HPRD | 19651622 | ||
| S80 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 17924679 | ||
| S87 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17322306, 18578522, 18491316, ... | ||
| S88 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19413330, 18491316, 20230923, ... | ||
| S91 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S92 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19651622 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T8 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 20058876, ... | ||
| S24 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 17924679 | ||
| S25 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S33 | Phosphorylation | score0 | HPRD | 19651622 | ||
| S34 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 17924679 | ||
| S41 | Phosphorylation | score0 | HPRD | 17322306, 18578522, 18491316, ... | ||
| S42 | Phosphorylation | score0 | HPRD | 19413330, 17322306, 18491316, ... | ||
| S46 | Phosphorylation | score0 | HPRD | 19651622 | ||
| S85 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 17081983, ... | ||
| S94 | Phosphorylation | score0 | HPRD | 17081983 |
PTM-dependent PPI
| PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
|---|---|---|---|---|---|---|---|
| Phosphorylation | P49841 (GSK3B) | S9 | Q9UK76 (JPT1) | unknown | eFIP | 25169422 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K8 | Q8 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S14 | N14 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R22 | W22 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| R22 | Q22 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S46 | F46 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S92 | F92 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc, cosmic, icgc ] | |
| S94 | P94 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S140 | P140 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View