Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UK13 / ZN221_HUMAN
Protein Name Zinc finger protein 221
Gene Name Name: ZNF221
Organism Homo sapiens (Human)

PRO ID PR:Q9UK13
DAG View
PRO Name zinc finger protein 221 (human)
Definition A zinc finger protein 221 that is encoded in the genome of human.
Short Label hZNF221
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UK13 (ZNF221) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K22 Acetylation PhosphoSitePlus
K22 Sumoylation PhosphoSitePlus
K53 Sumoylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
T277 Phosphorylation PhosphoSitePlus
K280 Sumoylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
T305 Phosphorylation PhosphoSitePlus
T333 Phosphorylation PhosphoSitePlus
K367 Sumoylation PhosphoSitePlus
T389 Phosphorylation PhosphoSitePlus
K423 Sumoylation PhosphoSitePlus
Y432 Phosphorylation PhosphoSitePlus
T473 Phosphorylation PhosphoSitePlus
K495 Sumoylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
K504 Acetylation PhosphoSitePlus
K504 Sumoylation PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
K507 Sumoylation PhosphoSitePlus
K535 Sumoylation PhosphoSitePlus
K579 Sumoylation PhosphoSitePlus
S605 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T333 I333 Biomuta DOID:3963 / thyroid carcinoma [ cosmic ]
T389 S389 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K423 I423 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K507 I507 Biomuta DOID:2596 / larynx cancer [ cosmic ]
K507 T507 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K535 T535 Biomuta DOID:1793 / pancreatic cancer [ tcga ]