iPTMnet Report for Q9UJY1 (HSPB8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UJY1 / HSPB8_HUMAN
Protein Name Heat shock protein beta-8
Gene Name Name: HSPB8
Synonyms:CRYAC,E2IG1,HSP22;ORFNames:PP1629;
Organism Homo sapiens (Human)

PRO ID PR:Q9UJY1
DAG View
PRO Name heat shock protein beta-8 (human)
Definition A heat shock protein beta-8 that is encoded in the genome of human.
Short Label hHSPB8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UJY1 (HSPB8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation P17252 (PRKCA) HPRD   phospho.ELM   PhosphoSitePlus   Signor 22721717, 11342557
S24 Phosphorylation P27361 (MAPK3) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21526341, ...18220336
S27 Phosphorylation P27361 (MAPK3) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 22721717, 11342557, 18212344, ...21526341
S57 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus 18298377
T63 O-Glycosylation GlyGen 30379171, 22564745, 16408927
T63 Phosphorylation P17252 (PRKCA) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 22721717, 11342557, 18212344, ...11816564
S66 O-Glycosylation GlyGen 30379171, 22564745, 16408927
R71 Methylation PhosphoSitePlus
R78 Methylation PhosphoSitePlus
T87 Phosphorylation P27361 (MAPK3) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 22721717, 11342557, 20068231, ...21526341
S104 Phosphorylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
Y118 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
S122 Phosphorylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
S159 Phosphorylation P27361 (MAPK3) neXtProt 21526341
Y174 Phosphorylation IEDB 35494241


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S14 I14 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S24 C24 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S66 L66 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R71 Q71 Biomuta DOID:1612 / breast cancer [ cosmic ]
S122 F122 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]