iPTMnet Report for Q9UJX5 (ANAPC4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UJX5 / APC4_HUMAN
Protein Name Anaphase-promoting complex subunit 4
Gene Name Name: ANAPC4
Synonyms:APC4;
Organism Homo sapiens (Human)

PRO ID PR:Q9UJX5
DAG View
PRO Name anaphase-promoting complex subunit 4 (human)
Definition An anaphase-promoting complex subunit 4 that is encoded in the genome of human.
Short Label hANAPC4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UJX5 (ANAPC4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R3 Methylation PhosphoSitePlus
T87 Phosphorylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
T199 Phosphorylation PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
T429 Phosphorylation PhosphoSitePlus
T441 Phosphorylation PhosphoSitePlus
T446 Phosphorylation PhosphoSitePlus
K468 Ubiquitination PhosphoSitePlus
Y469 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 14657031
S488 Phosphorylation PhosphoSitePlus
K508 Ubiquitination PhosphoSitePlus
Y516 Phosphorylation PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
K526 Ubiquitination PhosphoSitePlus
Y625 Phosphorylation PhosphoSitePlus
T627 Phosphorylation PhosphoSitePlus
T628 Phosphorylation PhosphoSitePlus
K630 Acetylation PhosphoSitePlus
S736 Phosphorylation PhosphoSitePlus
S757 Phosphorylation PhosphoSitePlus   UniProt 19690332
S758 Phosphorylation PhosphoSitePlus   UniProt 19690332
K772 Sumoylation PhosphoSitePlus
S777 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 23186163, ...19690332
S779 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 14657031
S779 Phosphorylation P06493 (CDK1) PhosphoSitePlus 14657031
S779 Phosphorylation P53350 (PLK1) phospho.ELM   PhosphoSitePlus 14657031
K798 Sumoylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S736 Phosphorylation HPRD 18452278
S777 Phosphorylation HPRD 18669648, 20068231, 18452278
S779 Phosphorylation HPRD 19413330, 18669648, 18452278


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:O60566 (hBUB1B) Interaction PR:Q9UJX5 (hANAPC4) PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K147 N147 Biomuta DOID:1324 / lung cancer [ cosmic ]
T204 I204 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y469 H469 Biomuta DOID:3571 / liver cancer [ cosmic ]
K526 N526 Biomuta DOID:1324 / lung cancer [ cosmic ]