iPTMnet Report for Q9UJX4 (ANAPC5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UJX4 / APC5_HUMAN
Protein Name Anaphase-promoting complex subunit 5
Gene Name Name: ANAPC5
Synonyms:APC5;
Organism Homo sapiens (Human)

PRO ID PR:Q9UJX4
DAG View
PRO Name anaphase-promoting complex subunit 5 (human)
Definition An anaphase-promoting complex subunit 5 that is encoded in the genome of human.
Short Label hANAPC5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UJX4 (ANAPC5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T15 Phosphorylation PhosphoSitePlus
T47 Phosphorylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
C86 Methylation IEDB 31844290
K167 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
T178 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S179 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S195 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 14657031, 22067460
S202 Phosphorylation phospho.ELM 15302935
K210 Ubiquitination PhosphoSitePlus
S217 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S221 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
K224 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
T232 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 23186163
S235 Phosphorylation PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
Y255 Phosphorylation PhosphoSitePlus
Y258 Phosphorylation PhosphoSitePlus
Y277 Phosphorylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
C339 Methylation IEDB 31844290
K366 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
S421 Phosphorylation PhosphoSitePlus
C471 Methylation IEDB 31844290
K524 Ubiquitination PhosphoSitePlus
K547 Ubiquitination PhosphoSitePlus
K562 Ubiquitination PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
S596 Phosphorylation PhosphoSitePlus
T598 Phosphorylation PhosphoSitePlus
K669 Ubiquitination PhosphoSitePlus
S674 Phosphorylation PhosphoSitePlus
K682 Ubiquitination PhosphoSitePlus
K683 Ubiquitination PhosphoSitePlus
K698 Ubiquitination PhosphoSitePlus
K703 Ubiquitination PhosphoSitePlus
K726 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T178 Phosphorylation HPRD 19007248
S217 Phosphorylation HPRD 15302935
S413 Phosphorylation HPRD 20068231
S421 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T15 N15 Biomuta DOID:3571 / liver cancer [ cosmic ]
K77 T77 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K77 I77 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S202 Y202 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
C339 Y339 Biomuta DOID:4159 / skin cancer [ cosmic ]
K366 M366 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K397 R397 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K403 M403 Biomuta DOID:1324 / lung cancer [ cosmic ]
K403 N403 Biomuta DOID:363 / uterine cancer [ icgc ]
K403 Q403 Biomuta DOID:363 / uterine cancer [ icgc ]
S421 R421 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K669 R669 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K682 Q682 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]