Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UJX3 / APC7_HUMAN
Protein Name Anaphase-promoting complex subunit 7
Gene Name Name: ANAPC7
Synonyms:APC7;
Organism Homo sapiens (Human)

PRO ID PR:Q9UJX3
DAG View
PRO Name anaphase-promoting complex subunit 7 (human)
Definition An anaphase-promoting complex subunit 7 that is encoded in the genome of human.
Short Label hANAPC7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UJX3 (ANAPC7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S51 Phosphorylation P53350 (PLK1) PhosphoSitePlus 14657031
S57 Phosphorylation P53350 (PLK1) PhosphoSitePlus 14657031
S58 Phosphorylation PhosphoSitePlus
T62 Phosphorylation PhosphoSitePlus
S64 Phosphorylation P53350 (PLK1) PhosphoSitePlus 14657031
Y77 Phosphorylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
T120 Phosphorylation PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
T126 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
K263 Acetylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
Y311 Phosphorylation PhosphoSitePlus
Y313 Phosphorylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
Y360 Phosphorylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
Y434 Phosphorylation PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K467 Acetylation PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
Y475 Phosphorylation PhosphoSitePlus
K477 Ubiquitination PhosphoSitePlus
K482 Ubiquitination PhosphoSitePlus
K491 Ubiquitination PhosphoSitePlus
K551 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S119 Phosphorylation HPRD 18669648
S125 Phosphorylation HPRD 18669648
T126 Phosphorylation HPRD 18669648


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:O60566 (hBUB1B) Interaction PR:Q9UJX3 (hANAPC7) PRO
PR:O60566 (hBUB1B) Interaction PR:Q9UJX3 (hANAPC7) PRO
PR:O60566 (hBUB1B) Interaction PR:Q9UJX3 (hANAPC7) PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T120 P120 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S129 R129 Biomuta DOID:363 / uterine cancer [ icgc, tcga ]
K263 I263 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y360 C360 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
K364 N364 Biomuta DOID:363 / uterine cancer [ tcga ]
K462 R462 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
K467 T467 Biomuta DOID:363 / uterine cancer [ tcga ]
K491 N491 Biomuta DOID:4362 / cervical cancer [ tcga ]