iPTMnet Report for Q9UJX2 (CDC23)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UJX2 / CDC23_HUMAN
Protein Name Cell division cycle protein 23 homolog
Gene Name Name: CDC23
Synonyms:ANAPC8;
Organism Homo sapiens (Human)

PRO ID PR:Q9UJX2
DAG View
PRO Name cell division cycle protein 23 homolog (human)
Definition A cell division cycle protein 23 that is encoded in the genome of human.
Short Label hCDC23
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UJX2 (CDC23) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
S21 Phosphorylation PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
Y115 Phosphorylation PhosphoSitePlus
Y120 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
K147 Sumoylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
Y273 Phosphorylation PhosphoSitePlus   UniProt 14657031
K281 Ubiquitination PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
Y329 Phosphorylation PhosphoSitePlus
Y340 Phosphorylation PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
Y353 Phosphorylation PhosphoSitePlus
K359 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
C442 Methylation IEDB 31844290
K445 Ubiquitination PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
Y460 Phosphorylation PhosphoSitePlus
K467 Acetylation PhosphoSitePlus   UniProt 19608861
K467 Ubiquitination PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus
C489 Methylation IEDB 31844290
K522 Methylation PhosphoSitePlus
K524 Ubiquitination PhosphoSitePlus
S530 Phosphorylation PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
T542 Phosphorylation PhosphoSitePlus
K547 Ubiquitination PhosphoSitePlus
T562 O-Glycosylation GlyGen 32119511, 34725712, 28657654, ...35254053
T562 Phosphorylation P53350 (PLK1) , P06493 (CDK1) neXtProt   PhosphoSitePlus   UniProt 14657031, 18669648
T564 Phosphorylation PhosphoSitePlus
T565 O-Glycosylation GlyGen 32119511, 34725712, 30620550, ...28657654, 35254053
T565 Phosphorylation P53350 (PLK1) , P06493 (CDK1) PhosphoSitePlus   Signor   UniProt 14657031
S576 O-Glycosylation GlyGen 32119511, 34725712, 28657654, ...35254053
S576 Phosphorylation PhosphoSitePlus
S578 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T582 Phosphorylation PhosphoSitePlus   UniProt 18669648, 19690332
T584 Phosphorylation PhosphoSitePlus
S588 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18691976, 21406692, 23186163, ...16964243, 22067460, 18669648, 24275569, 33863878, 32387766, 19690332, 20068231
S593 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S594 Phosphorylation PhosphoSitePlus
T596 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 24275569, 19690332, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S304 Phosphorylation HPRD 20068231
Y308 Phosphorylation HPRD 20068231
T562 Phosphorylation HPRD 18669648, 19007248, 20068231
T564 Phosphorylation HPRD 18669648
T565 Phosphorylation HPRD 18669648
S576 Phosphorylation HPRD 18691976, 18669648, 20068231
S578 Phosphorylation HPRD 18691976, 18669648, 15345747, ...20068231
T582 Phosphorylation HPRD 18669648, 20068231
T584 Phosphorylation HPRD 18669648
S588 Phosphorylation HPRD 19413330, 18691976, 18212344, ...18767875, 15302935, 19664995, 16565220, 19651622, 19664994, 18669648, 20068231, 16964243
S593 Phosphorylation HPRD 19651622, 18669648, 17081983
S594 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
T596 Phosphorylation HPRD 19413330, 18691976, 16964243, ...18767875, 16565220, 19651622, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y115 C115 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S121 F121 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ]
Y273 C273 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K313 T313 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K535 R535 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S578 P578 Biomuta DOID:1324 / lung cancer [ cosmic ]
T582 P582 Biomuta DOID:1612 / breast cancer [ cosmic ]