Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UJW0 / DCTN4_HUMAN
Protein Name Dynactin subunit 4
Gene Name Name: DCTN4
Organism Homo sapiens (Human)

PRO ID PR:Q9UJW0
DAG View
PRO Name dynactin subunit 4 (human)
Definition A dynactin subunit 4 that is encoded in the genome of human.
Short Label hDCTN4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UJW0 (DCTN4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
R9 Methylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
T101 Phosphorylation PhosphoSitePlus
Y107 Phosphorylation PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K146 Sumoylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
Y173 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
Y182 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus   UniProt 23186163
T199 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
K206 Acetylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
Y376 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 E2 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y107 C107 Biomuta DOID:1612 / breast cancer [ icgc ]
K146 E146 Biomuta DOID:1324 / lung cancer [ cosmic ]
S179 L179 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
Y182 H182 Biomuta DOID:363 / uterine cancer [ tcga ]
T199 I199 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S204 F204 Biomuta DOID:363 / uterine cancer [ tcga ]
K215 T215 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
Y376 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]