iPTMnet Report for Q9UJV9 (DDX41)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UJV9 / DDX41_HUMAN
Protein Name Probable ATP-dependent RNA helicase DDX41
Gene Name Name: DDX41
Synonyms:ABS;
Organism Homo sapiens (Human)

PRO ID PR:Q9UJV9
DAG View
PRO Name probable ATP-dependent RNA helicase DDX41 (human)
Definition A probable ATP-dependent RNA helicase DDX41 that is encoded in the genome of human.
Short Label hDDX41
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UJV9 (DDX41) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus   UniProt 23186163
K9 Sumoylation PhosphoSitePlus
K9 Ubiquitination PRO
T13 Phosphorylation PhosphoSitePlus
S21 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 15302935, ...18452278, 19651622, 18669648, 19690332, 20068231
S23 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 18220336, ...19664994, 15302935, 18452278, 18669648, 16565220, 19690332, 20068231
Y33 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K49 Ubiquitination PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
R71 Methylation PhosphoSitePlus
S83 Phosphorylation HPRD 17081983
S86 Phosphorylation HPRD 17081983
K95 Ubiquitination PhosphoSitePlus
K111 Sumoylation PhosphoSitePlus
K115 Ubiquitination PRO   PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
Y138 Phosphorylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
T147 Phosphorylation PhosphoSitePlus
R194 Methylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
T320 Phosphorylation PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
C338 Methylation IEDB 31844290
Y364 Phosphorylation Q06187 (BTK) PhosphoSitePlus 25704810
K366 Methylation PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
K392 Sumoylation PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
T395 Phosphorylation PhosphoSitePlus
Y414 Phosphorylation Q06187 (BTK) PhosphoSitePlus   RLIMS-P 25704810, 27502187
K416 Sumoylation PhosphoSitePlus
K416 Ubiquitination PhosphoSitePlus
K442 Sumoylation PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
K455 Ubiquitination PhosphoSitePlus
K466 Ubiquitination PhosphoSitePlus
K473 Ubiquitination PhosphoSitePlus
K482 Ubiquitination PhosphoSitePlus
T533 Phosphorylation HPRD 20068231
K538 Ubiquitination PhosphoSitePlus
K549 Ubiquitination PhosphoSitePlus
K556 Ubiquitination PhosphoSitePlus
C568 Methylation IEDB 31844290
K597 Ubiquitination PhosphoSitePlus
T603 Phosphorylation PhosphoSitePlus
K604 Ubiquitination PhosphoSitePlus
K612 Ubiquitination PhosphoSitePlus
S619 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047158 (hDDX41/Ubiq:1) ubK115 PRO
PR:000047159 (hDDX41/Ubiq:2) ubK9 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R71 Q71 Biomuta DOID:1612 / breast cancer [ icgc ] DOID:11054 / urinary bladder cancer [ icgc ]
K556 E556 Biomuta DOID:10534 / stomach cancer [ icgc ]