iPTMnet Report for Q9UJF2 (RASAL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UJF2 / NGAP_HUMAN
Protein Name Ras GTPase-activating protein nGAP
Gene Name Name: RASAL2
Synonyms:NGAP;
Organism Homo sapiens (Human)

PRO ID PR:Q9UJF2
DAG View
PRO Name Ras GTPase-activating protein nGAP (human)
Definition A Ras GTPase-activating protein nGAP that is encoded in the genome of human.
Short Label hRASAL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UJF2 (RASAL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus   UniProt 18669648, 24275569
S18 Phosphorylation PhosphoSitePlus
T20 Phosphorylation PhosphoSitePlus
K25 Acetylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
T31 Phosphorylation PhosphoSitePlus
T34 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
K38 Acetylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
T64 Phosphorylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus   UniProt 18669648
S92 Phosphorylation PhosphoSitePlus
S95 Phosphorylation PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
Y246 Phosphorylation PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
Y381 Phosphorylation PhosphoSitePlus
Y389 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
Y566 Phosphorylation PhosphoSitePlus
K614 Ubiquitination PhosphoSitePlus
T617 Phosphorylation PhosphoSitePlus
T620 Phosphorylation PhosphoSitePlus   UniProt 23186163
T630 Phosphorylation PhosphoSitePlus
S634 Phosphorylation PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus
S639 Phosphorylation PhosphoSitePlus
S641 Phosphorylation PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus
K660 Ubiquitination PhosphoSitePlus
K662 Methylation PhosphoSitePlus
K662 Ubiquitination PhosphoSitePlus
S663 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S665 Phosphorylation PhosphoSitePlus
S671 Phosphorylation PhosphoSitePlus
Y672 Phosphorylation PhosphoSitePlus
S700 Phosphorylation PhosphoSitePlus
T734 Phosphorylation PhosphoSitePlus
S736 Phosphorylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
T741 Phosphorylation PhosphoSitePlus
S745 Phosphorylation PhosphoSitePlus
T755 Phosphorylation PhosphoSitePlus
S758 Phosphorylation PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
Y786 Phosphorylation PhosphoSitePlus
S803 Phosphorylation PhosphoSitePlus
S814 Phosphorylation PhosphoSitePlus
S830 Phosphorylation PhosphoSitePlus
S838 Phosphorylation PhosphoSitePlus
S841 Phosphorylation PhosphoSitePlus
T849 Phosphorylation PhosphoSitePlus
S864 Phosphorylation PhosphoSitePlus   UniProt 21406692
T865 Phosphorylation PhosphoSitePlus
K872 Acetylation PhosphoSitePlus
S887 Phosphorylation PhosphoSitePlus
S891 Phosphorylation PhosphoSitePlus
S893 Phosphorylation PhosphoSitePlus
S896 Phosphorylation PhosphoSitePlus
S899 Phosphorylation PhosphoSitePlus
S916 Phosphorylation PhosphoSitePlus
S918 Phosphorylation PhosphoSitePlus
S922 Phosphorylation PhosphoSitePlus
S923 Phosphorylation PhosphoSitePlus
S924 Phosphorylation PhosphoSitePlus
S925 Phosphorylation PhosphoSitePlus
S928 Phosphorylation PhosphoSitePlus
T941 Phosphorylation PhosphoSitePlus
S946 Phosphorylation PhosphoSitePlus
S954 Phosphorylation PhosphoSitePlus
Y1010 Phosphorylation PhosphoSitePlus
K1080 Acetylation PhosphoSitePlus
S1091 Phosphorylation PhosphoSitePlus
S1111 Phosphorylation PhosphoSitePlus
S1119 Phosphorylation PhosphoSitePlus
K1135 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation HPRD 17081983
S16 Phosphorylation HPRD 18669648
S35 Phosphorylation HPRD 19413330
S89 Phosphorylation HPRD 18669648
S95 Phosphorylation HPRD 18669648
S283 Phosphorylation HPRD 20068231
T620 Phosphorylation HPRD 19664994, 19664995
S663 Phosphorylation HPRD 18669648, 20068231
S665 Phosphorylation HPRD 18669648, 20068231
S758 Phosphorylation HPRD 19664994
S864 Phosphorylation HPRD 20068231
Y1010 Phosphorylation HPRD 19664994
S1119 Phosphorylation HPRD 18669648, 20068231
T1124 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S100 Phosphorylation PhosphoSitePlus
T132 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
S159 Phosphorylation HPRD   PhosphoSitePlus 18691976, 17081983
S164 Phosphorylation HPRD   PhosphoSitePlus 18669648
S183 Phosphorylation HPRD 19413330
S237 Phosphorylation HPRD   PhosphoSitePlus 18669648
S243 Phosphorylation HPRD 18669648
S351 Phosphorylation PhosphoSitePlus
S431 Phosphorylation HPRD 20068231
T761 Phosphorylation HPRD 19664994, 19664995
S804 Phosphorylation HPRD 18669648, 20068231
S806 Phosphorylation HPRD 18669648, 20068231
S899 Phosphorylation HPRD 19664994
S1005 Phosphorylation HPRD 20068231
Y1151 Phosphorylation HPRD 19664994
S1260 Phosphorylation HPRD 18669648, 20068231
T1265 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 F11 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S18 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S18 L18 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S28 F28 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S35 L35 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S35 P35 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S70 F70 Biomuta DOID:4159 / skin cancer [ cosmic ]
S159 F159 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S183 L183 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S183 P183 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y246 D246 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y381 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y389 N389 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T620 M620 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
T630 S630 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S634 F634 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S635 I635 Biomuta DOID:1324 / lung cancer [ cosmic ]
S671 N671 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T734 I734 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T761 M761 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S780 L780 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y786 H786 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S830 R830 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T849 M849 Biomuta DOID:363 / uterine cancer [ icgc ]
T865 A865 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S893 Y893 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S899 N899 Biomuta DOID:263 / kidney cancer [ cosmic ]
S922 F922 Biomuta DOID:4159 / skin cancer [ cosmic ]
S925 F925 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S928 G928 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y1010 * Biomuta DOID:4159 / skin cancer [ cosmic ]
Y1151 * Biomuta DOID:4159 / skin cancer [ cosmic ]