iPTMnet Report for Q9UJC3 (HOOK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UJC3 / HOOK1_HUMAN
Protein Name Protein Hook homolog 1
Gene Name Name: HOOK1
Organism Homo sapiens (Human)

PRO ID PR:Q9UJC3
DAG View
PRO Name protein Hook homolog 1 (human)
Definition A protein Hook homolog 1 that is encoded in the genome of human.
Short Label hHOOK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UJC3 (HOOK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
C31 Methylation IEDB 31844290
C111 Methylation IEDB 31844290
S167 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K194 Ubiquitination PhosphoSitePlus
S235 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 18669648, ...24275569, 20068231
K245 Ubiquitination PhosphoSitePlus
T299 Phosphorylation PhosphoSitePlus
R337 Methylation PhosphoSitePlus
K375 Acetylation PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus
C652 Methylation IEDB 31844290
T699 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16964243
S719 O-Glycosylation GlyGen 30379171, 29351928, 35254053, ...35138101, 30620550
S719 Phosphorylation PhosphoSitePlus   UniProt 21406692
T725 O-Glycosylation GlyGen 30379171, 29351928, 35254053, ...35138101, 30620550
T726 O-Glycosylation GlyGen 30379171, 29351928, 35254053, ...35138101, 30620550
S727 O-Glycosylation GlyGen 30379171, 29351928, 35254053, ...35138101, 30620550
S727 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S167 Phosphorylation HPRD 18669648
S235 Phosphorylation HPRD 19413330, 18669648, 16964243, ...20068231
T699 Phosphorylation HPRD 16964243


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R337 C337 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ]
C652 Y652 Biomuta DOID:1324 / lung cancer [ cosmic ]
C652 S652 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]