iPTMnet Report for Q9UIJ7 (AK3)
Protein Information
UniProt AC / UniProt ID | Q9UIJ7 / KAD3_HUMAN |
Protein Name | GTP:AMP phosphotransferase AK3, mitochondrial |
Gene Name | Name: AK3 Synonyms:AK3L1,AK6,AKL3L; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UIJ7 |
PRO Name | GTP:AMP phosphotransferase AK3, mitochondrial (human) |
Definition | A GTP:AMP phosphotransferase, mitochondrial that is encoded in the genome of human. |
Short Label | hAK3 |
Category | organism-gene |
Q9UIJ7 (AK3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S4 | Phosphorylation | score1 | PhosphoSitePlus | |||
S18 | O-Glycosylation | score1 | GlyGen | 33465208 | ||
K20 | Acetylation | score1 | PhosphoSitePlus | |||
K34 | Acetylation | score1 | PhosphoSitePlus | |||
S37 | Phosphorylation | score1 | PhosphoSitePlus | |||
R48 | Methylation | score1 | PhosphoSitePlus | |||
Y85 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y138 | Phosphorylation | score1 | PhosphoSitePlus | |||
T147 | Phosphorylation | score1 | PhosphoSitePlus | |||
T154 | Phosphorylation | score1 | PhosphoSitePlus | |||
K165 | Acetylation | score1 | PhosphoSitePlus | |||
K181 | Acetylation | score1 | PhosphoSitePlus | |||
K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y186 | Phosphorylation | score1 | PhosphoSitePlus | |||
K189 | Acetylation | score1 | PhosphoSitePlus | |||
K190 | Acetylation | score1 | PhosphoSitePlus | |||
S197 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y207 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y209 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S18 | W18 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
K189 | E189 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |