iPTMnet Report for Q9UIG0 (BAZ1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UIG0 / BAZ1B_HUMAN
Protein Name Tyrosine-protein kinase BAZ1B
Gene Name Name: BAZ1B
Synonyms:WBSC10,WBSCR10,WBSCR9,WSTF;
Organism Homo sapiens (Human)

PRO ID PR:Q9UIG0
DAG View
PRO Name tyrosine-protein kinase BAZ1B (human)
Definition A bromodomain adjacent to zinc finger domain protein 1B that is encoded in the genome of human.
Short Label hBAZ1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UIG0 (BAZ1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K14 Ubiquitination PhosphoSitePlus
T28 Phosphorylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
T61 Phosphorylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K151 Acetylation PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
S158 Phosphorylation P27361 (MAPK3) , P45984 (MAPK9) , Q16539 (MAPK14) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 18669648, 19776015
S160 Phosphorylation PhosphoSitePlus
S161 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S166 Phosphorylation PhosphoSitePlus
S167 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
K175 Acetylation PhosphoSitePlus
K175 Methylation PhosphoSitePlus
K181 Methylation PhosphoSitePlus
S189 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S197 Phosphorylation PhosphoSitePlus
T203 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
K216 Acetylation PhosphoSitePlus
K221 Acetylation PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
Y222 Phosphorylation PhosphoSitePlus
K225 Sumoylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
T266 Phosphorylation PhosphoSitePlus   UniProt 20068231
K280 Ubiquitination PhosphoSitePlus
Y282 Phosphorylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
Y296 Phosphorylation PhosphoSitePlus
K297 Acetylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
Y298 Phosphorylation PhosphoSitePlus
K306 Acetylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
S321 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K322 Ubiquitination PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
S326 Phosphorylation phospho.ELM 18669648
S327 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S330 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K335 Ubiquitination PhosphoSitePlus
K343 Ubiquitination PhosphoSitePlus
K344 Methylation PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
S345 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S347 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 20068231
S349 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
K352 Ubiquitination PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
S361 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...20068231
S374 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K386 Ubiquitination PhosphoSitePlus
K409 Acetylation PhosphoSitePlus
K416 Acetylation PhosphoSitePlus
K426 Acetylation PhosphoSitePlus
K429 Acetylation PhosphoSitePlus
T430 Phosphorylation PhosphoSitePlus
K432 Acetylation PhosphoSitePlus
K445 Ubiquitination PhosphoSitePlus
K449 Acetylation PhosphoSitePlus
T451 Phosphorylation PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
K501 Ubiquitination PhosphoSitePlus
S508 Phosphorylation PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
S699 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S705 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 21406692, ...19690332
S708 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935
T710 Phosphorylation PhosphoSitePlus
S716 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
T759 Phosphorylation PhosphoSitePlus
Y760 Phosphorylation PhosphoSitePlus
K778 Ubiquitination PhosphoSitePlus
K810 Acetylation PhosphoSitePlus
K817 Acetylation PhosphoSitePlus
K826 Sumoylation PhosphoSitePlus
T833 Phosphorylation PhosphoSitePlus
S840 Phosphorylation PhosphoSitePlus
K843 Ubiquitination PhosphoSitePlus
S844 Phosphorylation PhosphoSitePlus
K853 Sumoylation PhosphoSitePlus
K853 Ubiquitination PhosphoSitePlus
K864 Acetylation PhosphoSitePlus
K885 Ubiquitination PhosphoSitePlus
K893 Acetylation PhosphoSitePlus
K893 Ubiquitination PhosphoSitePlus
S932 Phosphorylation PhosphoSitePlus
Y935 Phosphorylation PhosphoSitePlus
K942 Ubiquitination PhosphoSitePlus
T945 Phosphorylation PhosphoSitePlus
S947 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...24275569
Y952 Phosphorylation PhosphoSitePlus
S966 Phosphorylation PhosphoSitePlus
T969 Phosphorylation PhosphoSitePlus
T973 Phosphorylation PhosphoSitePlus
T983 Phosphorylation PhosphoSitePlus
K1043 Ubiquitination PhosphoSitePlus
K1068 Ubiquitination PhosphoSitePlus
S1078 Phosphorylation PhosphoSitePlus
K1089 Sumoylation PhosphoSitePlus
K1089 Ubiquitination PhosphoSitePlus
K1107 Sumoylation PhosphoSitePlus
K1116 Acetylation PhosphoSitePlus
K1118 Acetylation PhosphoSitePlus
S1127 Phosphorylation PhosphoSitePlus
K1129 Sumoylation PhosphoSitePlus
S1147 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T1287 Phosphorylation IEDB 35494241
K1291 Ubiquitination PhosphoSitePlus
S1315 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K1318 Ubiquitination PhosphoSitePlus
K1335 Acetylation PhosphoSitePlus
K1335 Ubiquitination PhosphoSitePlus
S1338 Phosphorylation PhosphoSitePlus
S1342 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18669648, 17081983, ...20068231
K1347 Ubiquitination PhosphoSitePlus
K1354 Ubiquitination PhosphoSitePlus
S1468 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 15302935, 18669648, 24275569, 20068231
S1476 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S158 Phosphorylation HPRD 18669648
S160 Phosphorylation HPRD 17081983
S161 Phosphorylation HPRD 18669648
S167 Phosphorylation HPRD 17525332
S189 Phosphorylation HPRD 17081983, 20068231
T203 Phosphorylation HPRD 20068231
S204 Phosphorylation HPRD 20068231
T266 Phosphorylation HPRD 20068231, 18452278
S283 Phosphorylation HPRD 19691289
S312 Phosphorylation HPRD 19651622
S318 Phosphorylation HPRD 17081983
S321 Phosphorylation HPRD 18669648
S326 Phosphorylation HPRD 18669648
S327 Phosphorylation HPRD 18669648
S330 Phosphorylation HPRD 19413330, 18669648, 19007248, ...20068231
S345 Phosphorylation HPRD 18669648, 20068231
S347 Phosphorylation HPRD 18669648, 19007248, 20068231
S349 Phosphorylation HPRD 18669648, 19691289, 19007248, ...20068231, 20068230
S359 Phosphorylation HPRD 20068231
S361 Phosphorylation HPRD 17081983, 19691289, 18452278, ...19651622, 18669648, 20068231
S374 Phosphorylation HPRD 18669648
S508 Phosphorylation HPRD 19007248, 19691289
S699 Phosphorylation HPRD 18669648
S705 Phosphorylation HPRD 19651622, 18669648, 16565220, ...15302935, 18452278
S708 Phosphorylation HPRD 19651622, 18669648, 15302935, ...18452278
T710 Phosphorylation HPRD 18452278
S716 Phosphorylation HPRD 18669648
T945 Phosphorylation HPRD 17081983, 20068231
S947 Phosphorylation HPRD 18669648, 19691289
S1147 Phosphorylation HPRD 17081983
S1315 Phosphorylation HPRD 18669648
S1342 Phosphorylation HPRD 17081983, 19007248, 19691289, ...19651622, 18669648, 20068231
S1468 Phosphorylation HPRD 19413330, 18691976, 18491316, ...16565220, 15302935, 19664995, 19007248, 19651622, 18669648, 18707149, 18452278, 19415658, 20068231, 19691289


Q9UIG0 (BAZ1B) as PTM Enzyme



Substrate Site Score Source PMID
P16104 (H2AX) Y143 Signor 19092802


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T28 A28 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S46 R46 Biomuta DOID:363 / uterine cancer [ cosmic ]
S58 G58 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S161 N161 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T203 S203 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S204 L204 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K216 I216 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K231 T231 Biomuta DOID:363 / uterine cancer [ icgc ]
K231 N231 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S234 N234 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K250 N250 Biomuta DOID:4159 / skin cancer [ cosmic ]
S347 G347 Biomuta DOID:1319 / brain cancer [ cosmic ]
S349 L349 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ]
S374 L374 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K432 Q432 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K432 I432 Biomuta DOID:1324 / lung cancer [ cosmic ]
K483 N483 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S840 C840 Biomuta DOID:1324 / lung cancer [ cosmic ]
T973 S973 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T973 I973 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K1107 T1107 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1116 M1116 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K1118 N1118 Biomuta DOID:1612 / breast cancer [ cosmic ]