Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UIF7 / MUTYH_HUMAN
Protein Name Adenine DNA glycosylase
Gene Name Name: MUTYH
Synonyms:MYH;
Organism Homo sapiens (Human)

PRO ID PR:Q9UIF7
DAG View
PRO Name adenine DNA glycosylase (human)
Definition An adenine DNA glycosylase MUTYH that is encoded in the genome of human.
Short Label hMUTYH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UIF7 (MUTYH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
Y494 Phosphorylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
K506 Ubiquitination PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
S535 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 18491316
S9 Phosphorylation HPRD 18491316
Site PTM Type PTM Enzyme Score Source PMID
K41 Ubiquitination PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K27 Ubiquitination PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 A6 Biomuta DOID:1909 / melanoma [ cosmic ]
S512 F512 Biomuta DOID:3571 / liver cancer [ icgc ]
S535 C535 Biomuta DOID:10534 / stomach cancer [ cosmic ]