iPTMnet Report for Q9UIC8 (LCMT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UIC8 / LCMT1_HUMAN
Protein Name Leucine carboxyl methyltransferase 1
Gene Name Name: LCMT1
Synonyms:LCMT;ORFNames:CGI-68;
Organism Homo sapiens (Human)

PRO ID PR:Q9UIC8
DAG View
PRO Name leucine carboxyl methyltransferase 1 (human)
Definition A leucine carboxyl methyltransferase 1 that is encoded in the genome of human.
Short Label hLCMT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UIC8 (LCMT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
T11 Phosphorylation PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
T16 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
K181 Acetylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S9 P9 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S9 C9 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K109 N109 Biomuta DOID:363 / uterine cancer [ icgc ]
S277 L277 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]