iPTMnet Report for Q9UI95 (MAD2L2)
Protein Information
| UniProt AC / UniProt ID | Q9UI95 / MD2L2_HUMAN |
| Protein Name | Mitotic spindle assembly checkpoint protein MAD2B |
| Gene Name | Name: MAD2L2 Synonyms:MAD2B,REV7; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UI95 |
| PRO Name | mitotic spindle assembly checkpoint protein MAD2B (human) |
| Definition | A mitotic spindle assembly checkpoint protein MAD2B that is encoded in the genome of human. |
| Short Label | hMAD2L2 |
| Category | organism-gene |
DAG ViewQ9UI95 (MAD2L2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C20 | Methylation | score1 | IEDB | 31844290 | ||
| K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K90 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K162 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K167 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T191 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K72 | Q72 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K162 | N162 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
