iPTMnet Report Q9UI30 TRMT112

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9UI30 / TR112_HUMAN
Protein Name	Multifunctional methyltransferase subunit TRM112-like protein
Gene Name	Name: TRMT112 ORFNames:AD-001,HSPC152,HSPC170;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9UI30 DAG View
PRO Name	multifunctional methyltransferase subunit TRM112-like protein (human)
Definition	A multifunctional methyltransferase subunit TRM112-like protein that is encoded in the genome of human.
Short Label	hTRMT112
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9UI30 (TRMT112) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K2	Sumoylation		score1	PhosphoSitePlus
	K2	Ubiquitination		score1	PhosphoSitePlus
	T5	Phosphorylation		score1	PhosphoSitePlus
	R14	Methylation		score1	PhosphoSitePlus
	R24	Methylation		score1	PhosphoSitePlus
	C33	Methylation		score1	IEDB	31844290
	C33	S-Nitrosylation		score0	dbSNO	19483679
	K48	Ubiquitination		score1	PhosphoSitePlus
	K68	Ubiquitination		score1	PhosphoSitePlus
	Y74	Phosphorylation		score1	PhosphoSitePlus
	S119	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 19690332, 20068231
	S125	Phosphorylation		score2	PhosphoSitePlus UniProt	20068231

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	M1	Acetylation		score1	PRO
	S119	Phosphorylation		score0	HPRD	17322306, 19651622, 18669648, ...20068231
	S125	Phosphorylation		score0	HPRD	19651622, 20068231

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000036362 (hTRMT112/Ac:1)	acM1		PRO

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
R14	L14	Biomuta		DOID:1319 / brain cancer [ cosmic, icgc ]