iPTMnet Report for Q9UI17 (DMGDH)
Protein Information
| UniProt AC / UniProt ID | Q9UI17 / M2GD_HUMAN |
| Protein Name | Dimethylglycine dehydrogenase, mitochondrial precursor |
| Gene Name | Name: DMGDH |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UI17 |
| PRO Name | dimethylglycine dehydrogenase, mitochondrial (human) |
| Definition | A dimethylglycine dehydrogenase, mitochondrial that is encoded in the genome of human. |
| Short Label | hDMGDH |
| Category | organism-gene |
DAG ViewQ9UI17 (DMGDH) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K37 | Acetylation | score1 | PhosphoSitePlus | |||
| K118 | Acetylation | score1 | PhosphoSitePlus | |||
| Y215 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T220 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S238 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K360 | Acetylation | score1 | PhosphoSitePlus | |||
| T373 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y374 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S508 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K574 | Acetylation | score1 | PhosphoSitePlus | |||
| S597 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T645 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y695 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T373 | M373 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K574 | N574 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| Y695 | H695 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y695 | C695 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
