iPTMnet Report for Q9UHY8 (FEZ2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UHY8 / FEZ2_HUMAN
Protein Name Fasciculation and elongation protein zeta-2
Gene Name Name: FEZ2
Organism Homo sapiens (Human)

PRO ID PR:Q9UHY8
DAG View
PRO Name fasciculation and elongation protein zeta-2 (human)
Definition A fasciculation and elongation protein zeta-2 that is encoded in the genome of human.
Short Label hFEZ2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UHY8 (FEZ2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S29 Phosphorylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
T111 Phosphorylation PhosphoSitePlus
T118 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus   UniProt 24275569
S176 Phosphorylation PhosphoSitePlus   UniProt 24275569
S195 Phosphorylation PhosphoSitePlus   UniProt 23186163
T200 O-Glycosylation GlyGen 30379171
T200 Phosphorylation PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
Y209 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
T230 Phosphorylation PhosphoSitePlus
T301 Phosphorylation PhosphoSitePlus
T304 Phosphorylation PhosphoSitePlus
T305 Phosphorylation PhosphoSitePlus
Y309 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S135 Phosphorylation HPRD 19664994
S195 Phosphorylation HPRD 18077418
Site PTM Type PTM Enzyme Score Source PMID
S135 Phosphorylation HPRD 19664994
S195 Phosphorylation HPRD 18077418


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S109 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
S135 L135 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S195 F195 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S205 C205 Biomuta DOID:1324 / lung cancer [ cosmic ]
S217 * Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]