Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UHY1 / NRBP_HUMAN
Protein Name Nuclear receptor-binding protein
Gene Name Name: NRBP1
Synonyms:BCON3;
Organism Homo sapiens (Human)

PRO ID PR:Q9UHY1
DAG View
PRO Name nuclear receptor-binding protein (human)
Definition A nuclear receptor-binding protein that is encoded in the genome of human.
Short Label hNRBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UHY1 (NRBP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 21406692, 22223895, ...20068231
S2 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...17081983, 19007248, 19651622, 20068231
S6 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
T8 Phosphorylation HPRD   PhosphoSitePlus 17081983
S11 Phosphorylation PhosphoSitePlus
S12 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20068231
S14 Phosphorylation HPRD   PhosphoSitePlus 19651622
S49 Phosphorylation PhosphoSitePlus
K131 Acetylation PhosphoSitePlus
K134 Acetylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
Y152 Phosphorylation PhosphoSitePlus
T225 Phosphorylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
T232 Phosphorylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
S422 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S428 Phosphorylation PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
T431 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 17287340, 20058876, ...19664994, 19651622, 18669648
T433 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18088087, 16964243, ...19664994, 20058876, 19664995, 18452278, 19651622, 18669648, 17287340, 23186163, 15345747, 19690332
K471 Ubiquitination PhosphoSitePlus
S505 O-Glycosylation GlyGen 23301498, 28510447, 35254053, ...30379171, 34725712, 34019948, 30059200, 35132862, 30620550, 31492838, 32119511, 29351928, 28657654
K517 Ubiquitination PhosphoSitePlus
T532 O-Glycosylation GlyGen 23301498, 28510447, 35254053, ...30379171, 34725712, 34019948, 30059200, 35132862, 30620550, 31492838, 32119511, 29351928, 28657654
S534 O-Glycosylation GlyGen 23301498, 28510447, 35254053, ...30379171, 34725712, 34019948, 30059200, 35132862, 30620550, 31492838, 32119511, 29351928, 28657654
S535 O-Glycosylation GlyGen 23301498, 28510447, 35254053, ...30379171, 34725712, 34019948, 30059200, 35132862, 30620550, 31492838, 32119511, 29351928, 28657654
S535 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 F6 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T8 S8 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S11 N11 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S14 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K131 T131 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K131 R131 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y152 F152 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y152 C152 Biomuta DOID:363 / uterine cancer [ icgc ]
S363 C363 Biomuta DOID:1324 / lung cancer [ cosmic ]
K517 T517 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T532 P532 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S534 F534 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S535 F535 Biomuta DOID:4159 / skin cancer [ cosmic ]