iPTMnet Report for Q9UHX1 (PUF60)
Protein Information
UniProt AC / UniProt ID | Q9UHX1 / PUF60_HUMAN |
Protein Name | Poly(U)-binding-splicing factor PUF60 |
Gene Name | Name: PUF60 Synonyms:FIR; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UHX1 |
PRO Name | poly(U)-binding-splicing factor PUF60 (human) |
Definition | A poly(U)-binding-splicing factor PUF60 that is encoded in the genome of human. |
Short Label | hPUF60 |
Category | organism-gene |
Q9UHX1 (PUF60) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T3 | Phosphorylation | score1 | PhosphoSitePlus | |||
T5 | Phosphorylation | score1 | PhosphoSitePlus | |||
K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
K43 | Sumoylation | score1 | PhosphoSitePlus | |||
T60 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 16964243, ... | ||
K69 | Ubiquitination | score1 | PhosphoSitePlus | |||
K72 | Methylation | score1 | PhosphoSitePlus | |||
K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y73 | Phosphorylation | score1 | PhosphoSitePlus | |||
K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
S112 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
S116 | Phosphorylation | score1 | PhosphoSitePlus | |||
C129 | Methylation | score1 | IEDB | 31844290 | ||
K168 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y177 | Phosphorylation | score1 | PhosphoSitePlus | |||
K201 | Ubiquitination | score1 | PhosphoSitePlus | |||
S206 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S238 | Phosphorylation | score1 | PhosphoSitePlus | |||
K243 | Ubiquitination | score1 | PhosphoSitePlus | |||
S244 | Phosphorylation | score1 | PhosphoSitePlus | |||
K251 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K251 | Ubiquitination | score1 | PhosphoSitePlus | |||
T262 | Phosphorylation | score1 | PhosphoSitePlus | |||
T263 | Phosphorylation | score1 | PhosphoSitePlus | |||
K267 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y274 | Phosphorylation | score1 | PhosphoSitePlus | |||
S280 | Phosphorylation | score1 | PhosphoSitePlus | |||
K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
T304 | Phosphorylation | score1 | PhosphoSitePlus | |||
T311 | Phosphorylation | score1 | PhosphoSitePlus | |||
T314 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 20068231 | ||
S406 | Phosphorylation | score1 | PhosphoSitePlus | |||
K454 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K454 | Ubiquitination | score1 | PhosphoSitePlus | |||
K458 | Sumoylation | score1 | PhosphoSitePlus | |||
T462 | Phosphorylation | score1 | PhosphoSitePlus | |||
K489 | Ubiquitination | score1 | PhosphoSitePlus | |||
K541 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y547 | Phosphorylation | score1 | PhosphoSitePlus | |||
S555 | Phosphorylation | score1 | PhosphoSitePlus | |||
S558 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T3 | Phosphorylation | score0 | HPRD | 18491316 | ||
T60 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 20068231 | ||
S112 | Phosphorylation | score0 | HPRD | 20068231 | ||
S206 | Phosphorylation | score0 | HPRD | 18669648 | ||
T311 | Phosphorylation | score0 | HPRD | 20068231 | ||
T314 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S406 | Phosphorylation | score0 | HPRD | 20058876 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T3 | Phosphorylation | score0 | HPRD | 18491316 | ||
T60 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 20068231 | ||
T87 | Phosphorylation | score1 | PhosphoSitePlus | |||
S189 | Phosphorylation | score0 | HPRD | 18669648 | ||
T294 | Phosphorylation | score0 | HPRD | 20068231 | ||
T297 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S389 | Phosphorylation | score0 | HPRD | 20058876 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K14 | Sumoylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K14 | Sumoylation | score1 | PhosphoSitePlus | |||
T58 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K34 | N34 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T60 | A60 | Biomuta | DOID:4362 / cervical cancer [ cosmic ] | |
T60 | M60 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S112 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K168 | N168 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
Y177 | C177 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S189 | R189 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S206 | R206 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S389 | N389 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:4362 / cervical cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
S406 | N406 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K489 | N489 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S558 | C558 | Biomuta | DOID:1612 / breast cancer [ cosmic ] |