iPTMnet Report for Q9UHQ9 (CYB5R1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UHQ9 / NB5R1_HUMAN
Protein Name NADH-cytochrome b5 reductase 1
Gene Name Name: CYB5R1
Synonyms:NQO3A2;ORFNames:UNQ3049/PRO9865;
Organism Homo sapiens (Human)

PRO ID PR:Q9UHQ9
DAG View
PRO Name NADH-cytochrome b5 reductase 1 (human)
Definition An NADH-cytochrome b5 reductase 1 that is encoded in the genome of human.
Short Label hCYB5R1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UHQ9 (CYB5R1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K54 Ubiquitination PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
Y84 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K130 Methylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
S132 O-Glycosylation GlyGen 30620550
S137 O-Glycosylation GlyGen 30620550
K139 Methylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
K167 Acetylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
T186 Phosphorylation HPRD   PhosphoSitePlus 20068231
T189 Phosphorylation HPRD   PhosphoSitePlus 20068231
K200 Ubiquitination PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
T258 Phosphorylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K130 N130 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S150 I150 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K167 N167 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]