iPTMnet Report for Q9UHL9 (GTF2IRD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UHL9 / GT2D1_HUMAN
Protein Name General transcription factor II-I repeat domain-containing protein 1
Gene Name Name: GTF2IRD1
Synonyms:CREAM1,GTF3,MUSTRD1,RBAP2,WBSCR11,WBSCR12;
Organism Homo sapiens (Human)

PRO ID PR:Q9UHL9
DAG View
PRO Name general transcription factor II-I repeat domain-containing protein 1 (human)
Definition A general transcription factor II-I repeat domain-containing protein 1 that is encoded in the genome of human.
Short Label hGTF2IRD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UHL9 (GTF2IRD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K94 Ubiquitination PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K212 Sumoylation PhosphoSitePlus
K225 Sumoylation PhosphoSitePlus
K271 Sumoylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K308 Sumoylation PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
K337 Sumoylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K379 Sumoylation PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
T403 Phosphorylation PhosphoSitePlus
Y404 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
K436 Sumoylation PhosphoSitePlus
K436 Ubiquitination PhosphoSitePlus
K443 Sumoylation PhosphoSitePlus
K443 Ubiquitination PhosphoSitePlus
S448 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 15302935, ...18669648, 20068231
T461 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus
S477 Phosphorylation PhosphoSitePlus
K495 Sumoylation PhosphoSitePlus
K567 Sumoylation PhosphoSitePlus
Y577 Phosphorylation PhosphoSitePlus
K579 Sumoylation PhosphoSitePlus
K579 Ubiquitination PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus
K638 Sumoylation PhosphoSitePlus
S654 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
K684 Sumoylation PhosphoSitePlus
K684 Ubiquitination PhosphoSitePlus
Q686 Phosphorylation UniProt 17525332
T704 Phosphorylation PhosphoSitePlus
K715 Ubiquitination PhosphoSitePlus
K716 Ubiquitination PhosphoSitePlus
Y717 Phosphorylation PhosphoSitePlus
K724 Sumoylation PhosphoSitePlus
K724 Ubiquitination PhosphoSitePlus
K754 Ubiquitination PhosphoSitePlus
K787 Sumoylation PhosphoSitePlus
K799 Ubiquitination PhosphoSitePlus
K807 Ubiquitination PhosphoSitePlus
Y814 Phosphorylation PhosphoSitePlus
Y828 Phosphorylation PhosphoSitePlus
K829 Sumoylation PhosphoSitePlus
K829 Ubiquitination PhosphoSitePlus
S834 Phosphorylation PhosphoSitePlus
S906 Phosphorylation PhosphoSitePlus
S914 Phosphorylation PhosphoSitePlus
S915 Phosphorylation PhosphoSitePlus
S916 Phosphorylation PhosphoSitePlus
S917 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y404 Phosphorylation HPRD 20068231
S448 Phosphorylation HPRD 18669648, 15302935, 20068231, ...18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K201 R201 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K271 N271 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y404 F404 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K495 N495 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y577 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K716 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K754 N754 Biomuta DOID:1324 / lung cancer [ cosmic ]
K787 Q787 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K799 Q799 Biomuta DOID:1319 / brain cancer [ cosmic ]
K807 M807 Biomuta DOID:3571 / liver cancer [ cosmic ]
S906 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S914 F914 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S916 L916 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]