Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9UHK6 / AMACR_HUMAN
Protein Name Alpha-methylacyl-CoA racemase
Gene Name Name: AMACR
Organism Homo sapiens (Human)

DAG View
PRO Name alpha-methylacyl-CoA racemase (human)
Definition An alpha-methylacyl-CoA racemase that is encoded in the genome of human.
Short Label hAMACR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9UHK6 (AMACR) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K58 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
Y126 Phosphorylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
Y365 Phosphorylation PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S115 Phosphorylation PhosphoSitePlus
Y126 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
T153 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y126 C126 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
Y126 N126 Biomuta DOID:363 / uterine cancer [ tcga ]