iPTMnet Report for Q9UHI8 (ADAMTS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UHI8 / ATS1_HUMAN
Protein Name A disintegrin and metalloproteinase with thrombospondin motifs 1 precursor
Gene Name Name: ADAMTS1
Synonyms:KIAA1346,METH1;
Organism Homo sapiens (Human)

PRO ID PR:Q9UHI8
DAG View
PRO Name a disintegrin and metalloproteinase with thrombospondin motifs 1 (human)
Definition An a disintegrin and metalloproteinase with thrombospondin motifs 1 that is encoded in the genome of human.
Short Label hADAMTS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UHI8 (ADAMTS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation PhosphoSitePlus
C123 Methylation IEDB 31844290
T170 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T197 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T208 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T574 Phosphorylation PhosphoSitePlus
Y581 Phosphorylation PhosphoSitePlus
T582 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus
T732 Phosphorylation PhosphoSitePlus
K735 Ubiquitination PhosphoSitePlus
Y738 Phosphorylation PhosphoSitePlus
T749 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T197 M197 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T574 M574 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T582 M582 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]