iPTMnet Report for Q9UHI6 (DDX20)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UHI6 / DDX20_HUMAN
Protein Name Probable ATP-dependent RNA helicase DDX20
Gene Name Name: DDX20
Synonyms:DP103,GEMIN3;
Organism Homo sapiens (Human)

PRO ID PR:Q9UHI6
DAG View
PRO Name probable ATP-dependent RNA helicase DDX20 (human)
Definition A probable ATP-dependent RNA helicase DDX20 that is encoded in the genome of human.
Short Label hDDX20
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UHI6 (DDX20) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S86 Phosphorylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus   UniProt 18691976
K192 Ubiquitination PhosphoSitePlus
Y199 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus   UniProt 23186163
S269 Phosphorylation PhosphoSitePlus   UniProt 23186163
S272 Phosphorylation PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
K354 Ubiquitination PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
T461 Phosphorylation PhosphoSitePlus
Y462 Phosphorylation PhosphoSitePlus
K473 Ubiquitination PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
K487 Methylation PhosphoSitePlus
K487 Ubiquitination PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus
S500 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243
S505 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
K507 Ubiquitination PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus
S522 Phosphorylation PhosphoSitePlus
C524 Methylation IEDB 31844290
K529 Ubiquitination PhosphoSitePlus
T531 Phosphorylation PhosphoSitePlus
S532 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K534 Ubiquitination PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
T552 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163
S560 Phosphorylation PhosphoSitePlus   UniProt 23186163
K565 Ubiquitination PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
Y616 Phosphorylation PhosphoSitePlus
K634 Ubiquitination PhosphoSitePlus
S649 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S652 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S654 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S656 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K671 Ubiquitination PhosphoSitePlus
S672 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...20068231
Y673 Phosphorylation PhosphoSitePlus
S677 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 19690332
S678 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 19690332, 20068231
S685 Phosphorylation PhosphoSitePlus
T688 Phosphorylation PhosphoSitePlus   UniProt 16964243
R693 Methylation PhosphoSitePlus
S695 Phosphorylation PhosphoSitePlus
S703 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
T705 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 15302935
K710 Ubiquitination PhosphoSitePlus
Y711 Phosphorylation PhosphoSitePlus
S714 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 15302935, ...18669648, 20068231
K720 Methylation PhosphoSitePlus
K720 Ubiquitination PhosphoSitePlus
S728 Phosphorylation PhosphoSitePlus
S742 Phosphorylation PhosphoSitePlus
S743 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus 27920218, 17081983
T748 Phosphorylation PhosphoSitePlus
Y756 Phosphorylation PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus
Y770 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S47 Phosphorylation HPRD 18691976
S48 Phosphorylation HPRD 18691976, 18669648, 20068231
S86 Phosphorylation HPRD 20068231
S187 Phosphorylation HPRD 17322306, 18691976, 20068231
S268 Phosphorylation HPRD 19691289
S272 Phosphorylation HPRD 20068231
S500 Phosphorylation HPRD 18669648, 16964243, 20068231, ...19691289
S502 Phosphorylation HPRD 20068231
S532 Phosphorylation HPRD 18669648
S549 Phosphorylation HPRD 20068231
T552 Phosphorylation HPRD 18691976, 18669648, 19691289, ...20068231
S557 Phosphorylation HPRD 20068231
S560 Phosphorylation HPRD 20068231
S649 Phosphorylation HPRD 18669648
S652 Phosphorylation HPRD 18669648
S654 Phosphorylation HPRD 18669648
S656 Phosphorylation HPRD 18669648
S672 Phosphorylation HPRD 18691976, 17081983, 19691289, ...19651622, 18669648, 20068231
Y673 Phosphorylation HPRD 19413330, 17081983
S677 Phosphorylation HPRD 19413330, 18691976, 18767875, ...19651622, 17322306, 18669648, 20068231
S678 Phosphorylation HPRD 19413330, 18691976, 18767875, ...19664994, 19691289, 19664995, 17322306, 18669648, 19651622, 20068231
T688 Phosphorylation HPRD 16964243
S703 Phosphorylation HPRD 19413330, 19664994, 19664995, ...19651622, 18669648, 20068231
T705 Phosphorylation HPRD 19413330, 18691976, 18767875, ...15302935, 19664995, 19651622, 18669648, 20068231
S714 Phosphorylation HPRD 19413330, 18691976, 18767875, ...19664994, 19007248, 19664995, 17322306, 18669648, 20068231, 19691289


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S86 L86 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K91 M91 Biomuta DOID:4159 / skin cancer [ cosmic ]
S320 N320 Biomuta DOID:363 / uterine cancer [ cosmic ]
S505 L505 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T531 P531 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K608 E608 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K608 T608 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y616 H616 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K634 N634 Biomuta DOID:1324 / lung cancer [ cosmic ]
S672 L672 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S685 Y685 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T688 M688 Biomuta DOID:263 / kidney cancer [ cosmic ]
R693 H693 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:2531 / hematologic cancer [ cosmic ]
R693 S693 Biomuta [ cosmic ] DOID:1793 / pancreatic cancer [ cosmic ]
S714 L714 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S743 Y743 Biomuta DOID:1612 / breast cancer [ icgc ]