Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UHG0 / DCDC2_HUMAN
Protein Name Doublecortin domain-containing protein 2
Gene Name Name: DCDC2
Synonyms:KIAA1154,RU2;
Organism Homo sapiens (Human)

PRO ID PR:Q9UHG0
DAG View
PRO Name doublecortin domain-containing protein 2 (human)
Definition A doublecortin domain-containing protein 2 that is encoded in the genome of human.
Short Label hDCDC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UHG0 (DCDC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation PhosphoSitePlus
Y22 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
Y99 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
T229 Phosphorylation PhosphoSitePlus
S247 Phosphorylation PhosphoSitePlus
K251 Methylation PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
T382 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y99 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y22 * Biomuta DOID:3571 / liver cancer [ icgc ]
S43 N43 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S128 L128 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S221 G221 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S221 I221 Biomuta DOID:3571 / liver cancer [ tcga ]
S221 N221 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S247 F247 Biomuta DOID:4362 / cervical cancer [ tcga ] DOID:5041 / esophageal cancer [ icgc ]
S269 L269 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S300 P300 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
T382 I382 Biomuta DOID:363 / uterine cancer [ tcga ]
S438 T438 Biomuta DOID:10534 / stomach cancer [ cosmic ]