Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9UHD1 / CHRD1_HUMAN
Protein Name Cysteine and histidine-rich domain-containing protein 1
Gene Name Name: CHORDC1
Organism Homo sapiens (Human)

DAG View
PRO Name cysteine and histidine-rich domain-containing protein 1 (human)
Definition A cysteine and histidine-rich domain-containing protein 1 that is encoded in the genome of human.
Short Label hCHORDC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9UHD1 (CHORDC1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
R8 Methylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
Y26 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
T47 Phosphorylation PhosphoSitePlus   UniProt 18669648
T48 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus   UniProt 18669648
C59 S-Nitrosylation dbSNO 26338901
K68 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K89 Acetylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
Y178 Phosphorylation PhosphoSitePlus
K198 Acetylation PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
T199 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
T212 Phosphorylation PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K220 Acetylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
Y292 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T47 Phosphorylation HPRD 18669648, 20068231
T48 Phosphorylation HPRD 18669648
S51 Phosphorylation HPRD 18669648
S200 Phosphorylation HPRD 19413330

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 S2 Biomuta DOID:1324 / lung cancer [ cosmic ]
R8 W8 Biomuta DOID:3070 / malignant glioma [ tcga ]
C59 F59 Biomuta DOID:1324 / lung cancer [ cosmic ]
K89 E89 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K101 T101 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K107 Q107 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S110 G110 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S110 R110 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S137 L137 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K198 N198 Biomuta DOID:363 / uterine cancer [ tcga ]
T212 A212 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K289 M289 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S314 G314 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]