iPTMnet Report for Q9UHC9 (NPC1L1)
Protein Information
| UniProt AC / UniProt ID | Q9UHC9 / NPCL1_HUMAN |
| Protein Name | NPC1-like intracellular cholesterol transporter 1 precursor |
| Gene Name | Name: NPC1L1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UHC9 |
| PRO Name | NPC1-like intracellular cholesterol transporter 1 (human) |
| Definition | An NPC1-like intracellular cholesterol transporter 1 that is encoded in the genome of human. |
| Short Label | hNPC1L1 |
| Category | organism-gene |
DAG ViewQ9UHC9 (NPC1L1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N54 | N-Glycosylation | score3 | GlyGen UniProt | 21525977 | ||
| S56 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N138 | N-Glycosylation | score3 | GlyGen UniProt | 21525977 | ||
| S433 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S658 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1232 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1337 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S433 | N433 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S1205 | F1205 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
| T1232 | A1232 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S1337 | N1337 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S1337 | R1337 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] |
