iPTMnet Report for Q9UHB9 (SRP68)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UHB9 / SRP68_HUMAN
Protein Name Signal recognition particle subunit SRP68
Gene Name Name: SRP68
Organism Homo sapiens (Human)

PRO ID PR:Q9UHB9
DAG View
PRO Name signal recognition particle subunit SRP68 (human)
Definition A signal recognition particle subunit SRP68 that is encoded in the genome of human.
Short Label hSRP68
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UHB9 (SRP68) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Acetylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
R31 Methylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
S48 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087
K49 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus   UniProt 23186163
S267 Phosphorylation PhosphoSitePlus
T270 Phosphorylation PhosphoSitePlus
K277 Acetylation PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
C344 Methylation IEDB 31844290
K360 Ubiquitination PhosphoSitePlus
Y364 Phosphorylation PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
Y385 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K416 Acetylation PhosphoSitePlus
K416 Ubiquitination PhosphoSitePlus
K452 Acetylation PhosphoSitePlus   UniProt 19608861
K452 Ubiquitination PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
K491 Ubiquitination PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
K508 Ubiquitination PhosphoSitePlus
T518 Phosphorylation PhosphoSitePlus
K524 Ubiquitination PhosphoSitePlus
T543 Phosphorylation PhosphoSitePlus
C562 S-Nitrosylation dbSNO 19483679
T611 Phosphorylation PhosphoSitePlus
K612 Ubiquitination PhosphoSitePlus
Y618 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
S627 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation HPRD 20068231
S27 Phosphorylation HPRD 18691976
S48 Phosphorylation HPRD 18088087
S241 Phosphorylation HPRD 18691976
T518 Phosphorylation HPRD 20068231
Y618 Phosphorylation HPRD 18083107
S627 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S16 G16 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S27 N27 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S48 L48 Biomuta DOID:4159 / skin cancer [ cosmic ]
S294 T294 Biomuta DOID:2998 / testicular cancer [ cosmic ]
K306 R306 Biomuta DOID:263 / kidney cancer [ cosmic ]
K360 R360 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K416 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K457 N457 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K491 Q491 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
K504 N504 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K524 N524 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S627 G627 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]