iPTMnet Report for Q9UGV2 (NDRG3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UGV2 / NDRG3_HUMAN
Protein Name Protein NDRG3
Gene Name Name: NDRG3
Organism Homo sapiens (Human)

PRO ID PR:Q9UGV2
DAG View
PRO Name protein NDRG3 (human)
Definition A protein NDRG3 that is encoded in the genome of human.
Short Label hNDRG3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UGV2 (NDRG3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378
K13 Ubiquitination PhosphoSitePlus
C166 Methylation IEDB 31844290
T183 Phosphorylation IEDB 35494241
K286 Ubiquitination PhosphoSitePlus
Y308 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
T322 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S327 Phosphorylation PhosphoSitePlus
T329 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S331 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...24275569
T332 O-Glycosylation GlyGen 23301498, 29351928
T332 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S333 Phosphorylation PhosphoSitePlus
S334 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S335 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S338 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S341 Phosphorylation PhosphoSitePlus   UniProt 23186163
S344 Phosphorylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
T348 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S352 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T355 Phosphorylation PhosphoSitePlus   UniProt 23186163
S358 Phosphorylation PhosphoSitePlus
C359 S-Nitrosylation dbSNO 26338901
S361 Phosphorylation PhosphoSitePlus
T370 Phosphorylation PhosphoSitePlus
S374 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
C375 S-Nitrosylation dbSNO 26338901
Site PTM Type PTM Enzyme Score Source PMID
T322 Phosphorylation HPRD 18669648
T329 Phosphorylation HPRD 19651622, 18669648, 20068231
S331 Phosphorylation HPRD 19651622, 18767875, 18669648, ...20166139, 20068231
T332 Phosphorylation HPRD 18767875, 18669648
S333 Phosphorylation HPRD 18767875
S334 Phosphorylation HPRD 18767875, 18669648, 20068231
S335 Phosphorylation HPRD 18669648, 20068231
S338 Phosphorylation HPRD 17322306, 18669648
S346 Phosphorylation HPRD 17081983
T348 Phosphorylation HPRD 17081983
S352 Phosphorylation HPRD 19413330, 18669648, 17081983
T355 Phosphorylation HPRD 18077418
S361 Phosphorylation HPRD 19413330
S374 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T310 Phosphorylation HPRD 18669648
T317 Phosphorylation HPRD 19651622, 18669648, 20068231
S319 Phosphorylation HPRD 19651622, 18767875, 18669648, ...20166139, 20068231
T320 Phosphorylation HPRD 18767875, 18669648
S321 Phosphorylation HPRD 18767875
S322 Phosphorylation HPRD 18767875, 18669648, 20068231
S323 Phosphorylation HPRD 18669648, 20068231
S326 Phosphorylation HPRD 17322306, 18669648
S334 Phosphorylation HPRD 17081983
T336 Phosphorylation HPRD 17081983
S340 Phosphorylation HPRD 19413330, 18669648, 17081983
T343 Phosphorylation HPRD 18077418
S349 Phosphorylation HPRD 19413330
S362 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S320 I320 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S322 R322 Biomuta DOID:4159 / skin cancer [ cosmic ]
S334 R334 Biomuta DOID:4159 / skin cancer [ cosmic ]
S334 F334 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T336 N336 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S346 F346 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T348 N348 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S358 F358 Biomuta DOID:4159 / skin cancer [ cosmic ]