iPTMnet Report for Q9UGP8 (SEC63)
Protein Information
| UniProt AC / UniProt ID | Q9UGP8 / SEC63_HUMAN |
| Protein Name | Translocation protein SEC63 homolog |
| Gene Name | Name: SEC63 Synonyms:SEC63L; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UGP8 |
| PRO Name | translocation protein SEC63 homolog (human) |
| Definition | A translocation protein SEC63 that is encoded in the genome of human. |
| Short Label | hSEC63 |
| Category | organism-gene |
Q9UGP8 (SEC63) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y106 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K130 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y149 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T153 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S157 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T269 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S283 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| K287 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K288 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K300 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S307 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K313 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K327 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C366 | Methylation | score1 | IEDB | 31844290 | ||
| K381 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K402 | Methylation | score1 | PhosphoSitePlus | |||
| K403 | Methylation | score1 | PhosphoSitePlus | |||
| K407 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K416 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S451 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T475 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T478 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S488 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K506 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K510 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K527 | Acetylation | score1 | PhosphoSitePlus | |||
| T537 | O-Glycosylation | score1 | GlyGen | 28510447, 33465208 | ||
| T537 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 20166139, 24275569, 18767875 | ||
| S544 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S570 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S574 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P Signor | 23287549 | ||
| S574 | Phosphorylation | P67870 (CSNK2B) | score1 | Signor | 23287549 | |
| S574 | Phosphorylation | P68400 (CSNK2A1) | score1 | Signor | 23287549 | |
| S576 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P Signor | 23287549 | ||
| S576 | Phosphorylation | P67870 (CSNK2B) | score1 | Signor | 23287549 | |
| S576 | Phosphorylation | P68400 (CSNK2A1) | score1 | Signor | 23287549 | |
| S593 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19651622 | ||
| S597 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19651622 | ||
| K607 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K623 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K631 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K633 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y642 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C671 | Methylation | score1 | IEDB | 31844290 | ||
| K688 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y692 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y694 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T695 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K710 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S742 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18669648 | ||
| S748 | Phosphorylation | score4 | HPRD PhosphoSitePlus RLIMS-P Signor UniProt | 18669648, 23287549 | ||
| S748 | Phosphorylation | P67870 (CSNK2B) | score1 | Signor | 23287549 | |
| S748 | Phosphorylation | P68400 (CSNK2A1) | score1 | Signor | 23287549 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y106 | D106 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T153 | M153 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| T269 | M269 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1725 / peritoneum cancer [ cosmic ] | |
| K327 | N327 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| K327 | T327 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S488 | C488 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| T537 | A537 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic ] DOID:1793 / pancreatic cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] | |
| K633 | N633 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| C671 | Y671 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y692 | F692 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K710 | Q710 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View