iPTMnet Report for Q9UGK8 (SERGEF)
Protein Information
UniProt AC / UniProt ID | Q9UGK8 / SRGEF_HUMAN |
Protein Name | Secretion-regulating guanine nucleotide exchange factor |
Gene Name | Name: SERGEF Synonyms:DELGEF,GNEFR; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UGK8 |
PRO Name | secretion-regulating guanine nucleotide exchange factor (human) |
Definition | A secretion-regulating guanine nucleotide exchange factor that is encoded in the genome of human. |
Short Label | hSERGEF |
Category | organism-gene |
Q9UGK8 (SERGEF) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
K201 | Ubiquitination | score1 | PhosphoSitePlus | |||
K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y304 | Phosphorylation | score1 | PhosphoSitePlus | |||
K308 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y416 | Phosphorylation | score1 | PhosphoSitePlus | |||
S418 | Phosphorylation | score1 | PhosphoSitePlus | |||
S427 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332, 23186163 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S418 | F418 | Biomuta | DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] |