Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UGJ0 / AAKG2_HUMAN
Protein Name 5'-AMP-activated protein kinase subunit gamma-2
Gene Name Name: PRKAG2
Organism Homo sapiens (Human)

PRO ID PR:Q9UGJ0
DAG View
PRO Name 5'-AMP-activated protein kinase subunit gamma-2 (human)
Definition A 5'-AMP-activated protein kinase subunit gamma-2 that is encoded in the genome of human.
Short Label hPRKAG2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UGJ0 (PRKAG2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S32 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
K62 Methylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus   UniProt 24275569
S73 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
T97 Phosphorylation PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
T156 Phosphorylation PhosphoSitePlus
S157 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S160 Phosphorylation PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus
S162 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S164 Phosphorylation PhosphoSitePlus
T165 Phosphorylation PhosphoSitePlus
T167 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
Y180 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
Y223 Phosphorylation PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S71 Phosphorylation HPRD 18691976
S129 Phosphorylation HPRD 19413330
S130 Phosphorylation HPRD 19413330
S135 Phosphorylation HPRD 20068231
S138 Phosphorylation HPRD 20068231
S143 Phosphorylation HPRD 19413330, 18691976
S157 Phosphorylation HPRD 17525332
S161 Phosphorylation HPRD 20068231
S162 Phosphorylation HPRD 19413330, 17525332
S164 Phosphorylation HPRD 19413330
T165 Phosphorylation HPRD 19413330
T167 Phosphorylation HPRD 17525332, 20068231
T170 Phosphorylation HPRD 20068231
S196 Phosphorylation HPRD 19413330, 18691976
Site PTM Type PTM Enzyme Score Source PMID
S27 Phosphorylation HPRD 18691976
S85 Phosphorylation HPRD 19413330
S86 Phosphorylation HPRD 19413330
S91 Phosphorylation HPRD 20068231
S94 Phosphorylation HPRD 20068231
S99 Phosphorylation HPRD 19413330, 18691976
S113 Phosphorylation HPRD 17525332
S117 Phosphorylation HPRD 20068231
S118 Phosphorylation HPRD 19413330, 17525332
S120 Phosphorylation HPRD 19413330
T121 Phosphorylation HPRD 19413330
T123 Phosphorylation HPRD 17525332, 20068231
T126 Phosphorylation HPRD 20068231
S152 Phosphorylation HPRD 19413330, 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S32 * Biomuta DOID:3571 / liver cancer [ icgc ]
S86 Y86 Biomuta DOID:1612 / breast cancer [ tcga ]
S161 F161 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T167 I167 Biomuta DOID:3070 / malignant glioma [ tcga ]
S196 F196 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S211 R211 Biomuta DOID:3571 / liver cancer [ icgc ]
S309 I309 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]