Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UFF9 / CNOT8_HUMAN
Protein Name CCR4-NOT transcription complex subunit 8
Gene Name Name: CNOT8
Synonyms:CALIF,POP2;
Organism Homo sapiens (Human)

PRO ID PR:Q9UFF9
DAG View
PRO Name CCR4-NOT transcription complex subunit 8 (human)
Definition A CCR4-NOT transcription complex subunit 8 that is encoded in the genome of human.
Short Label hCNOT8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UFF9 (CNOT8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K200 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
Y260 Phosphorylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K200 N200 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K206 N206 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K254 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K254 R254 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]