iPTMnet Report for Q9UER7 (DAXX)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UER7 / DAXX_HUMAN
Protein Name Death domain-associated protein 6
Gene Name Name: DAXX
Synonyms:BING2,DAP6;
Organism Homo sapiens (Human)

PRO ID PR:Q9UER7
DAG View
PRO Name death domain-associated protein 6 (human)
Definition A death domain-associated protein 6 that is encoded in the genome of human.
Short Label hDAXX
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UER7 (DAXX) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation PhosphoSitePlus   UniProt 24275569
S33 Phosphorylation PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
K60 Sumoylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
Y124 Phosphorylation PhosphoSitePlus
Y126 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
T169 Phosphorylation phospho.ELM 18669648
T174 Phosphorylation phospho.ELM 18669648
S176 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 18669648, 19789335, 19789334
S176 Phosphorylation Q99683 (MAP3K5) PhosphoSitePlus   Signor 19789334, 19789335
S178 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 17938171, 18669648, 23186163, ...18220336
S184 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 19789334, 19789335
S184 Phosphorylation Q99683 (MAP3K5) PhosphoSitePlus   Signor 19789334, 19789335
K208 Ubiquitination PhosphoSitePlus
S213 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K229 Ubiquitination PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
Y259 Phosphorylation PhosphoSitePlus
Y264 Phosphorylation PhosphoSitePlus
K277 Sumoylation PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K295 Sumoylation PhosphoSitePlus
Y334 Phosphorylation PhosphoSitePlus
Y344 Phosphorylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
Y379 Phosphorylation PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus
T408 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus   UniProt 23186163
S415 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 18077418, 23405218, 23186163
S424 Phosphorylation Q13535 (ATR) PhosphoSitePlus 18077418
S429 Phosphorylation PhosphoSitePlus
S495 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
S498 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
K506 Ubiquitination PhosphoSitePlus
K512 Acetylation PhosphoSitePlus   UniProt 19608861
K512 Sumoylation PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
S564 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor 23405218, 25659035
S564 Phosphorylation Q13315 (ATM) neXtProt   PhosphoSitePlus   Signor 23405218, 25659035
S618 Phosphorylation PhosphoSitePlus
K630 Sumoylation PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
K631 Sumoylation PhosphoSitePlus
K631 Ubiquitination PhosphoSitePlus
K637 Sumoylation PhosphoSitePlus
K637 Ubiquitination PhosphoSitePlus
T639 Phosphorylation PhosphoSitePlus
S641 Phosphorylation PhosphoSitePlus
S647 Phosphorylation PhosphoSitePlus
Y648 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S654 Phosphorylation PhosphoSitePlus
T665 Phosphorylation PhosphoSitePlus
S668 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 12968034, 18220336, 20565132, ...12529400, 18669648, 23260419, 15128734
S668 Phosphorylation Q86Z02 (HIPK1) neXtProt   Signor 12529400
S668 Phosphorylation Q9Y572 (RIPK3) PhosphoSitePlus 23260419
S671 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 18220336, 15302935, ...20565132, 18669648
S675 Phosphorylation PhosphoSitePlus
S683 Phosphorylation PhosphoSitePlus
S688 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 35561310, ...18220336
S690 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
T695 O-Glycosylation GlyGen 31373491
T695 Phosphorylation PhosphoSitePlus
S696 O-Glycosylation GlyGen 31373491
S696 Phosphorylation PhosphoSitePlus
S697 O-Glycosylation GlyGen 23301498, 30379171, 31373491
S702 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18220336, 18669648, 19690332, 20068231
S707 Phosphorylation PhosphoSitePlus   RLIMS-P 25659035
T709 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S712 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 17525332, 23405218, 25659035
T726 Phosphorylation RLIMS-P 25659035
S737 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17081983, 18669648, 21474068, ...19690332, 20068231
S737 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 21474068
S739 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17081983, 18669648, 21474068, ...19690332, 20068231
S739 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 21474068
Site PTM Type PTM Enzyme Score Source PMID
S97 Phosphorylation HPRD 20068231
T169 Phosphorylation HPRD 18669648
T174 Phosphorylation HPRD 18669648
S176 Phosphorylation HPRD 18669648
S178 Phosphorylation HPRD 18669648, 20068231
S213 Phosphorylation HPRD 18669648, 18452278
Y379 Phosphorylation HPRD 19664994
S424 Phosphorylation HPRD 18077418
S495 Phosphorylation HPRD 19413330, 17322306, 20230923, ...18767875, 18452278, 19651622, 18669648, 20068231
S498 Phosphorylation HPRD 20068231
S499 Phosphorylation HPRD 20068231
S515 Phosphorylation HPRD 20068231
Y648 Phosphorylation HPRD 17287340
T665 Phosphorylation HPRD 20068231
S668 Phosphorylation HPRD 17322306, 18669648, 20068231
S671 Phosphorylation HPRD 18669648, 15302935, 19664995, ...20068231
S675 Phosphorylation HPRD 20068231
S682 Phosphorylation HPRD 20068231
S688 Phosphorylation HPRD 19413330, 18669648, 16964243, ...20068231
S690 Phosphorylation HPRD 18669648, 20068231
S697 Phosphorylation HPRD 20068231
S702 Phosphorylation HPRD 19413330, 18669648, 16964243, ...20068231
T709 Phosphorylation HPRD 17525332
S712 Phosphorylation HPRD 17525332
S737 Phosphorylation HPRD 18669648, 17081983, 20068231, ...19415658
S739 Phosphorylation HPRD 18669648, 18452278, 19415658, ...20068231, 17081983


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9UER7 (DAXX) S564 Q00987 (MDM2) unknown eFIP 23405218


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:P29590-4 (hPML/iso:4) Interaction PR:Q9UER7-1 (hDAXX/iso:1) PRO 10669754
PR:Q92793-1 (hCREBBP/iso:1) Interaction PR:Q9UER7 (hDAXX) PRO 11799127