Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UEF7 / KLOT_HUMAN
Protein Name Klotho precursor
Gene Name Name: KL
Organism Homo sapiens (Human)

PRO ID PR:Q9UEF7
DAG View
PRO Name klotho (human)
Definition A klotho that is encoded in the genome of human.
Short Label hKL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UEF7 (KL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K499 Acetylation PhosphoSitePlus
K794 Acetylation PhosphoSitePlus
K942 Acetylation PhosphoSitePlus
S981 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S483 Phosphorylation HPRD 17322306


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K499 N499 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]