iPTMnet Report for Q9UEF7 (KL)
Protein Information
| UniProt AC / UniProt ID | Q9UEF7 / KLOT_HUMAN |
| Protein Name | Klotho precursor |
| Gene Name | Name: KL |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UEF7 |
| PRO Name | klotho (human) |
| Definition | A klotho that is encoded in the genome of human. |
| Short Label | hKL |
| Category | organism-gene |
DAG ViewQ9UEF7 (KL) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S115 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| N159 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| K499 | Acetylation | score1 | PhosphoSitePlus | |||
| K794 | Acetylation | score1 | PhosphoSitePlus | |||
| K942 | Acetylation | score1 | PhosphoSitePlus | |||
| S981 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S115 | L115 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| N159 | K159 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K499 | N499 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
