iPTMnet Report for Q9UDY4 (DNAJB4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UDY4 / DNJB4_HUMAN
Protein Name DnaJ homolog subfamily B member 4
Gene Name Name: DNAJB4
Synonyms:DNAJW,HLJ1;
Organism Homo sapiens (Human)

PRO ID PR:Q9UDY4
DAG View
PRO Name DnaJ homolog subfamily B member 4 (human)
Definition A DnaJ homolog subfamily B member 4 that is encoded in the genome of human.
Short Label hDNAJB4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UDY4 (DNAJB4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K13 Ubiquitination PhosphoSitePlus
Y24 Phosphorylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
S38 Phosphorylation HPRD   PhosphoSitePlus 20068231
K46 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
T79 Phosphorylation PhosphoSitePlus
T85 Phosphorylation PhosphoSitePlus
S122 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S133 Phosphorylation HPRD 20068231
S138 Phosphorylation HPRD 20068231
S148 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
S167 Phosphorylation PhosphoSitePlus
Y172 Phosphorylation PhosphoSitePlus   RLIMS-P 27065329
C175 Methylation IEDB 31844290
C175 S-Nitrosylation dbSNO 19483679
K177 Acetylation PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
T223 Phosphorylation HPRD   phospho.ELM 18669648
K236 Ubiquitination PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
Y252 Phosphorylation HPRD   PhosphoSitePlus 18452278
S280 Phosphorylation PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
Y296 Phosphorylation PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9UDY4 (DNAJB4) Y172 P12931 (SRC) unknown eFIP 27065329


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K13 R13 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S122 C122 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S138 R138 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S148 F148 Biomuta DOID:4159 / skin cancer [ cosmic ]
S148 P148 Biomuta DOID:363 / uterine cancer [ icgc ]
S167 L167 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T223 P223 Biomuta DOID:363 / uterine cancer [ icgc ]