Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UDR5 / AASS_HUMAN
Protein Name Alpha-aminoadipic semialdehyde synthase, mitochondrial precursor
Gene Name Name: AASS
Organism Homo sapiens (Human)

PRO ID PR:Q9UDR5
DAG View
PRO Name alpha-aminoadipic semialdehyde synthase, mitochondrial (human)
Definition An alpha-aminoadipic semialdehyde synthase, mitochondrial that is encoded in the genome of human.
Short Label hAASS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UDR5 (AASS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T51 Phosphorylation PhosphoSitePlus
Y55 Phosphorylation PhosphoSitePlus
K212 Acetylation PhosphoSitePlus
K229 Acetylation PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
Y461 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
T479 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
K539 Ubiquitination PhosphoSitePlus
Y556 Phosphorylation PhosphoSitePlus
Y700 Phosphorylation PhosphoSitePlus
K707 Acetylation PhosphoSitePlus
Y730 Phosphorylation PhosphoSitePlus
T878 Phosphorylation PhosphoSitePlus
K893 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T51 S51 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
Y55 C55 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
Y55 H55 Biomuta DOID:1324 / lung cancer [ cosmic ]
K229 N229 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T263 M263 Biomuta DOID:1612 / breast cancer [ icgc, tcga ] DOID:3070 / malignant glioma [ cosmic, tcga ]
T263 K263 Biomuta DOID:3571 / liver cancer [ icgc ]
K707 I707 Biomuta DOID:3070 / malignant glioma [ tcga ]
T878 I878 Biomuta DOID:1324 / lung cancer [ cosmic ]
T878 S878 Biomuta DOID:1324 / lung cancer [ cosmic ]
T878 P878 Biomuta DOID:1612 / breast cancer [ icgc ]