iPTMnet Report for Q9UBW8 (COPS7A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UBW8 / CSN7A_HUMAN
Protein Name COP9 signalosome complex subunit 7a
Gene Name Name: COPS7A
Synonyms:CSN7A,DERP10;
Organism Homo sapiens (Human)

PRO ID PR:Q9UBW8
DAG View
PRO Name COP9 signalosome complex subunit 7a (human)
Definition A COP9 signalosome complex subunit 7a that is encoded in the genome of human.
Short Label hCOPS7A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UBW8 (COPS7A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 18850735
K20 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
T219 Phosphorylation PhosphoSitePlus
K221 Acetylation PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
S232 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
T240 Phosphorylation PhosphoSitePlus
R243 Methylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
K256 Acetylation PhosphoSitePlus
K260 Acetylation PhosphoSitePlus
R265 Methylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K206 R206 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T219 I219 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T219 N219 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R243 K243 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
R265 * Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ]