iPTMnet Report for Q9UBU7 (DBF4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UBU7 / DBF4A_HUMAN
Protein Name Protein DBF4 homolog A
Gene Name Name: DBF4
Synonyms:ASK,DBF4A,ZDBF1;
Organism Homo sapiens (Human)

PRO ID PR:Q9UBU7
DAG View
PRO Name protein DBF4 homolog A (human)
Definition A protein DBF4 homolog A that is encoded in the genome of human.
Short Label hDBF4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UBU7 (DBF4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
K21 Sumoylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
Y177 Phosphorylation PhosphoSitePlus
T194 Phosphorylation PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
T210 O-Glycosylation GlyGen 30379171
T212 O-Glycosylation GlyGen 30379171
S260 Phosphorylation PhosphoSitePlus
T273 Phosphorylation IEDB   PhosphoSitePlus   UniProt 19369195, 23186163, 32157095
Y278 Phosphorylation PhosphoSitePlus
T281 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
Y303 Phosphorylation PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus   UniProt 23186163
T345 Phosphorylation PhosphoSitePlus   UniProt 19369195, 23186163
Y353 Phosphorylation PhosphoSitePlus
S354 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S357 Phosphorylation PhosphoSitePlus
S359 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 15302935, ...19690332
S362 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus   UniProt 19369195, 23186163
K393 Ubiquitination PhosphoSitePlus
K408 Sumoylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus   UniProt 19369195, 23186163
S420 Phosphorylation PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
T449 Phosphorylation Q13315 (ATM) , Q13535 (ATR) neXtProt   PhosphoSitePlus   Signor 22123827
K455 Ubiquitination PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
T468 Phosphorylation PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus
S502 Phosphorylation Q13315 (ATM) , Q13535 (ATR) neXtProt   PhosphoSitePlus   Signor 22123827
S508 Phosphorylation PhosphoSitePlus   UniProt 23186163
T510 Phosphorylation PhosphoSitePlus
T535 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S539 Phosphorylation Q13315 (ATM) , Q13535 (ATR) neXtProt   PhosphoSitePlus   Signor 22123827
T553 Phosphorylation PhosphoSitePlus   UniProt 23186163
S568 Phosphorylation PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus
K579 Sumoylation PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus
S613 Phosphorylation PhosphoSitePlus
S625 Phosphorylation UniProt 29997176
S629 Phosphorylation PhosphoSitePlus
T635 Phosphorylation PhosphoSitePlus
T638 Phosphorylation PhosphoSitePlus
C644 Methylation IEDB 31844290
S664 Phosphorylation PhosphoSitePlus
S665 Phosphorylation PhosphoSitePlus
S667 Phosphorylation UniProt 29997176
S669 Phosphorylation UniProt 29997176
Site PTM Type PTM Enzyme Score Source PMID
Y353 Phosphorylation HPRD 20068231
S354 Phosphorylation HPRD 18669648
S359 Phosphorylation HPRD 19413330, 18691976, 18767875, ...15302935, 19664995, 19651622, 18669648, 20068231
S381 Phosphorylation HPRD 19651622, 18691976, 17525332, ...20068231
S420 Phosphorylation HPRD 20068231
S508 Phosphorylation HPRD 20068231
T535 Phosphorylation HPRD 17525332
S539 Phosphorylation HPRD 17525332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T281 N281 Biomuta DOID:3571 / liver cancer [ cosmic ]
S357 F357 Biomuta DOID:263 / kidney cancer [ cosmic ]
S359 Y359 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S381 Y381 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S381 C381 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K408 R408 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S420 L420 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T510 N510 Biomuta DOID:1319 / brain cancer [ icgc ]
K579 E579 Biomuta DOID:1324 / lung cancer [ cosmic ]
S612 T612 Biomuta DOID:4159 / skin cancer [ cosmic ]
S613 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
C644 W644 Biomuta DOID:1319 / brain cancer [ cosmic ]
S664 L664 Biomuta DOID:363 / uterine cancer [ icgc ]