iPTMnet Report for Q9UBU2 (DKK2)
Protein Information
UniProt AC / UniProt ID | Q9UBU2 / DKK2_HUMAN |
Protein Name | Dickkopf-related protein 2 precursor |
Gene Name | Name: DKK2 ORFNames:UNQ682/PRO1316; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UBU2 |
PRO Name | dickkopf-related protein 2 (human) |
Definition | A dickkopf-related protein 2 that is encoded in the genome of human. |
Short Label | hDKK2 |
Category | organism-gene |
Q9UBU2 (DKK2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y58 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y89 | Phosphorylation | score1 | PhosphoSitePlus | |||
S92 | Phosphorylation | score1 | PhosphoSitePlus | |||
S97 | Phosphorylation | score1 | PhosphoSitePlus | |||
S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y155 | Phosphorylation | score1 | PhosphoSitePlus | |||
S156 | Phosphorylation | score1 | PhosphoSitePlus | |||
K250 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S97 | L97 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S98 | W98 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S98 | L98 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
S156 | L156 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K250 | E250 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |