iPTMnet Report for Q9UBR4 (LHX3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UBR4 / LHX3_HUMAN
Protein Name LIM/homeobox protein Lhx3
Gene Name Name: LHX3
Organism Homo sapiens (Human)

PRO ID PR:Q9UBR4
DAG View
PRO Name LIM/homeobox protein Lhx3 (human)
Definition A LIM/homeobox protein Lhx3 that is encoded in the genome of human.
Short Label hLHX3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UBR4 (LHX3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T63 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 15517599
S71 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 15517599
R159 Methylation PhosphoSitePlus
R161 Methylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
Y176 Phosphorylation PhosphoSitePlus
Y227 Phosphorylation PhosphoSitePlus   UniProt 15517599
S234 Phosphorylation PhosphoSitePlus   UniProt 15517599
S238 Phosphorylation PhosphoSitePlus   UniProt 15517599


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R159 W159 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R161 C161 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
R161 H161 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S174 R174 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y176 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]