iPTMnet Report for Q9UBP5 (HEY2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UBP5 / HEY2_HUMAN
Protein Name Hairy/enhancer-of-split related with YRPW motif protein 2
Gene Name Name: HEY2
Synonyms:BHLHB32,CHF1,GRL,HERP,HERP1,HRT2;
Organism Homo sapiens (Human)

PRO ID PR:Q9UBP5
DAG View
PRO Name hairy/enhancer-of-split related with YRPW motif protein 2 (human)
Definition A hairy/enhancer-of-split related with YRPW motif protein 2 that is encoded in the genome of human.
Short Label hHEY2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UBP5 (HEY2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S39 Phosphorylation PhosphoSitePlus
K58 Acetylation PhosphoSitePlus
T96 Phosphorylation PhosphoSitePlus
T131 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S139 F139 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S145 F145 Biomuta DOID:4159 / skin cancer [ cosmic ]
S207 A207 Biomuta DOID:363 / uterine cancer [ icgc ]