iPTMnet Report for Q9UBN4 (TRPC4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UBN4 / TRPC4_HUMAN
Protein Name Short transient receptor potential channel 4
Gene Name Name: TRPC4
Organism Homo sapiens (Human)

PRO ID PR:Q9UBN4
DAG View
PRO Name short transient receptor potential channel 4 (human)
Definition A short transient receptor potential cation channel TRPC4 that is encoded in the genome of human.
Short Label hTRPC4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UBN4 (TRPC4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S205 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
S390 O-Glycosylation GlyGen 29351928
Y624 Phosphorylation PhosphoSitePlus
S688 Phosphorylation PhosphoSitePlus   RLIMS-P 28124739
S781 Phosphorylation PhosphoSitePlus
S783 Phosphorylation PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus
S955 Phosphorylation PhosphoSitePlus
S956 Phosphorylation PhosphoSitePlus
Y959 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 21427121, 16144838
Y972 Phosphorylation PhosphoSitePlus   UniProt 16144838
Site PTM Type PTM Enzyme Score Source PMID
S193 Phosphorylation HPRD 17081983
S195 Phosphorylation HPRD 17081983


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:Q9UBN4-1 (hTRPC4/iso:Alpha) Interaction PRO 11713258
PR:Q9UBN4-2 (hTRPC4/iso:Beta) Interaction PRO 11713258


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S205 I205 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S390 T390 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S783 N783 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S956 G956 Biomuta DOID:1324 / lung cancer [ cosmic ]
S956 I956 Biomuta DOID:1324 / lung cancer [ cosmic ]
S956 N956 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]