iPTMnet Report for Q9UBB5 (MBD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UBB5 / MBD2_HUMAN
Protein Name Methyl-CpG-binding domain protein 2
Gene Name Name: MBD2
Organism Homo sapiens (Human)

PRO ID PR:Q9UBB5
DAG View
PRO Name methyl-CpG-binding domain protein 2 (human)
Definition A methyl-CpG-binding domain protein 2 that is encoded in the genome of human.
Short Label hMBD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UBB5 (MBD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R2 Methylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
R61 Methylation PhosphoSitePlus
K148 Acetylation PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
S181 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...32357974
S183 Phosphorylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K253 Acetylation PhosphoSitePlus
K253 Sumoylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
T296 Phosphorylation PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
S407 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 18669648, 24275569, ...19690332, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S168 Phosphorylation HPRD 20068231
S181 Phosphorylation HPRD 18669648, 20068231
S183 Phosphorylation HPRD 20068231
S407 Phosphorylation HPRD 19413330, 17081983, 18452278, ...19651622, 18669648, 19415658, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S168 Phosphorylation HPRD 20068231
S181 Phosphorylation HPRD 18669648, 20068231
S183 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S168 P168 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S183 R183 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S407 N407 Biomuta DOID:9256 / colorectal cancer [ cosmic, cosmic ] DOID:3571 / liver cancer [ cosmic ]